Thymectomy in Patients with Myasthenia Gravis
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Abstract:
A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
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Thymectomy in Myasthenia Gravis.
In recent years, thymectomy has become a widespread procedure in the treatment of myasthenia gravis (MG). Likelihood of remission was highest in preoperative mild disease classification (Osserman classification 1, 2A). In absence of thymoma or hyperplasia, there was no relationship between age and gender in remission with thymectomy. In MG treatment, randomized trials that compare conservative ...
full textThymectomy in myasthenia gravis.
Myasthenia gravis is an autoimmundisease characterized by muscle fatigability due to a reduction in available acetylcholinereceptors at neuromuscular junction. Although the role of the thymus in the pathophysiology remains obscure, the results of thymectomy are out of discussion. However, controversy continues concerning the indications for thymectomy. In a period of six years and a half, 24 pa...
full textThymectomy for Myasthenia Gravis.
Thymectomy was performed on 249 patients with myasthenia gravis between 1957 and 1981. During a follow-up period that ranged from 2 months to 24 years (mean 7.5 years), the remission rate for the entire group was 51 percent, and an additional 36 percent had improvement (87 percent benefited). In those 51 patients with thymoma, the remission rate was 37 percent, with 68 percent of the patients b...
full textThymectomy for myasthenia gravis
The pathophysiological role of the thymus in myasthenia gravis, and the mechanism of therapeutic effect of thymectomy, are incompletely understood. Nevertheless, thymectomy is a valuable treatment modality in selected patients with generalised myasthenia gravis. There are several types of thymectomy operation, but no one operative approach is clearly superior to the others. Total removal of the...
full textMYASTHENIA GRAVIS AND THYMECTOMY: A 10-YEAR STUDY IN SHIRAZ
A retrospective comparative study was performed on 54 patients treated medically or surgically (thymectomy) for myasthenia gravis (MG) from 1979- 1989 in three Shiraz University Hospitals. Each surgical patient was compared with a medical patient on the basis of age, sex, severity and duration of disease. Complete remission was noted in 3 out of 27 thymectomized patients but in none of the...
full textRespiratory crisis after thymectomy in patients with myasthenia gravis.
The term "crisis," as applied to myasthenia gravis, usually implies failure of the muscles concerned with respiration, obstruction of the airway due to weakness of the laryngeal and pharyngeal muscles, and the accumulation of salivary and bronchial secretions. It is in these circumstances that apparent resistance to antimyasthenic drugs sometimes develops. In recent years, thymectomy has been e...
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Journal title
volume 1 issue 4
pages 310- 312
publication date 1973-05
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